This is the Breakthrough Telomere Plus Stem Cell Support Supplement That Makes All Other Products Obsolete
"As a person who has been on the cutting edge of MANY fitness protocols and who was a key part of the initial launch of TA-65 I know this category like the back of my hand. TeloSC is the next evolution of longevity solutions and NOTHING combines telomere support with stem cell support. This makes all of the other products obsolete. It's like APPLE compared to IBM. Technology changes with the times and so do supplements." - Greta B., Los Angeles, CA
Call us Toll Free 800-881-5346
Email us: TSC@MaxLifeSolution.com
If you’re over 40 and want to undo the damage aging has caused you... pay attention.
If you REALLY want to look younger, enjoy a more vigorous sex life, and increase the number of quality years you can spend with those you love… then I have some truly fantastic news.
You’re about to be introduced to a revolutionary new anti-aging solution that targets the nastiest aspects of aging… including erasing years from your appearance, jacking up your energy and physical endurance, as well as making a massive influence on keeping nursing homes out of your future.
Hi, I'm David Kekich, one of the leading authorities on longevity science - - and the founder of MAXIMUM LIFE FOUNDATION.
Since 1999, my company has been a leader in the fight to reverse the human aging process.
Recently, in our efforts to crack the aging code, we took a big financial risk by betting on a controversial technology.
In fact, a $2 million Wall Street screw-up accidentally led to the world's most promising anti-aging marvel. (More on that in a moment). It can help shave decades off your biological age (that’s how old you appear to be)… and leave you feeling younger, sexier, and more vibrant… practically overnight.
This “agent” of anti-aging really works against our common enemy… aging.
But before I tell you about this anti-aging marvel, allow me to tell you my true story and reveal how a tragedy transformed my life and created in me the passion to undo aging.
Thirty eight years ago, a freak injury permanently paralyzed me.
In a blink of an eye, everything I thought was important to me seemed to vanish.
I remember it like it was yesterday. I was a rising young entrepreneur who had set up the largest master general life insurance agency in the country. As a long distance runner, dedicated weight training, vitamin popping health fanatic... I was in great shape.
I had an all-star girlfriend, an ocean front home and a new Mercedes convertible. I guess you could say I had it made.
Then, a twist of fate dramatically changed my life. And it directly affects you.
Let me explain.
I was working out in the gym when something popped. The next day, I found myself staring at the ceiling of a hospital room, connected to machines and monitors and unable to move or feel anything below my chest.
I had sustained a freak spinal cord injury and it has kept me confined to a wheelchair ever since.
My injury eventually cost me everything – my business, my ocean front home, my girlfriend... a complete personal and financial wipeout.
But worst of all, it cost me my attitude!
One minute, I was on top of the world - then suddenly, a hopeless paraplegic.
Let me tell you, I wasn’t much fun to be around for a long time after that. I was depressed, irritable... and even suicidal.
It took years to get over the shock.
Yet, in a strange way, lots of good came out of that sharp turn in my life. Besides giving me a much needed dose of humility, it made me much stronger emotionally.
Over time, my experience transformed me. It magnified my burning passion for life.
I developed the mindset of pushing myself to take on and overcome BIG challenges.
(Like how to help the 12,000 people per year who sustain spinal cord injuries to walk again.)
But along the way, I discovered that there was a MUCH BIGGER PROBLEM... namely the 37 million people a year who die “prematurely” from aging related causes.
So I decided to shift my mindset to take on what I saw as an even bigger challenge… aging.
Through sheer tenacity and being guided by some of the most renowned aging scientists in the world, I gained a unique insight into how to extend or even save the lives of the aging.
I spent twenty years leading an international research effort to develop a scientific roadmap to curb human aging. And as a result, I was accidently instrumental in developing breakthrough natural products that help keep you well, energetic… and youthful.
The Wall Street mistake I mentioned earlier was a blessing. It forced me to gamble on the new technology, that eclipses traditional nutritional supplement development capabilities.
It’s too complex to get into here, but it paid off BIG TIME.
Telomeres (red) are like caps at the end of your DNA strands that protect your chromosomes.
This new technology led to the formulation of the supplement TeloSC™ and although nothing can completely stop aging… at least not yet… what we did uncover was how to slow it down dramatically.
Even reverse much of it.
No matter what your age, your condition is not hopeless, because TeloSC can rejuvenate us… more completely than ANY other nutritional supplements on the market.
Maybe drugs, doctors and other methods haven’t worked for you?
TeloSC gives you a SECOND CHANCE for a vibrant, long, hearty life.
I won’t go a day without it.
What is TeloSC and Why Won’t I Go a Day without Taking It?
TeloSC delivers a one-two punch. The first punch comes by expanding your telomere health.
It does this by triggering gene activation.
Not only do the target cells receive proteins and nucleic acids that can help them self-repair, but it also activates genes within the target cells.
In fact, its ingredients DOUBLED the lifespan of simple lab animals in a clinical study.
Telomeres are protective pieces of DNA material at the ends of all your chromosomes.
But, with each cell division, they shorten.
And as they shorten you get old, sick… and die. Longer telomeres are associated with protection from age-related diseases, better cognitive function, and lipid profiles of healthy aging.
Telomerase is an enzyme. It protects cell health by extending your telomeres.
This discovery was so enormous that it won the 2009 Nobel Prize in Medicine because it’s leading to the ability to actually reverse aging.
This is the single greatest longevity development in our lifetime.
TeloSC is formulated to help cut the rate of telomere shortening and help restore telomeres to slow and aid in ultimately reversing aging. It does this by addressing ALL the ways telomeres shorten.
The second punch comes by up and restoring your stem cells.
And Stem Cells May Be the Biggest Thing EVER in the History of Medicine
Stem Cells are your body's built-in first aid kit.
You’re only as young as your stem cells. They repair every organ in your body… and help improve or normalize everything from your skin and eyesight to immune systems, heart repair and Alzheimer’s.
Think of them as mini-first aid kits for your damaged cells. Or think of the ability of a child to repair an injury vs. an adult.
Did You Know Our Bodies Constantly
Undergo Stem Cell Therapy?
You’d only live a day or two without your stem cells. Telomeres and stem cells form the foundation of cellular health. You need to maintain BOTH, because as a result of declining stem cell activity with ill health and age, average telomere length normally decreases.
After many generations, stem cells tend to become “senile.” In fact, as we age, stem cells weaken and dwindle by over 50%.
It was well put by Guenter Albrecht-Buehler at Northwestern University
Medical School when he said “Cells, not doctors heal patients.”
You see, only the cells of the patient can heal the patient. Only cells know how to close wounds, understand what to do with insulin and how to destroy pathogens.
The best a physician can do, is to move obstacles out of the way of cells (by surgery for example), supply materials and weapons to the cells (like drugs and building blocks of life) and leave the fight against disease to the cells.
Harnessing the power of the cells is the fundamental basis of Regenerative Medicine.
Dr. Allan C. Spradling of the Howard Hughes Medical Institute said: “no physician in the history of humanity has ever healed a patient.”
“Basically, our bodies are constantly undergoing stem cell therapy,” said Spradling.
“We would live one or two days without (adult) stem cells. It's essential to have these cells doing their thing.”
Now imagine the difference between a healthy flourishing tree and one that is dying or dead.
That’s the radical difference between healthy and unhealthy cells and the environment in which they live.
Your body without TeloSC is like a dying tree.
It’s a good representation of how most of us end up according to the choices we make. Without proper nourishment, all living things wither and die. And it brings home the contrast of the difference lifestyle choices make in our lives.
This is how TeloSC is created to help you on your way to optimal wellness.
It puts your body to work for you by both stimulating your adult stem cells to help repair aging-damaged tissues AND helps preserve your critical stem cell niche.
This allows your stem cells to thrive instead of withering.
So why invest in a telomere AND a stem cell support product when you can gain the benefits, convenience and cost savings of BOTH from one superior formulation?
Many telomere products alone cost 3-4 times more, and most are not proven to work as well as TeloSC.
Doesn’t a “Silver System” approach to your wellness make more sense than a “Silver Bullet?”
Even Billionaires Can’t Get A More Potent Longevity Product.
By consistently embracing this scientifically designed nutraceutical, you could slash years off your biological age by putting the genes to sleep that age you before your time.
Get this anti-aging product of the decade now.
It gives you broader and deeper rejuvenation (at any age) than any other supplement on the planet.
TeloSC is proven safe and effective for people facing the same aging challenges you face today.
Sure, other products make some of these claims, but thanks to a patent-pending technology, more of TeloSC’s ingredients get into your cells where they go to work much more effectively than other products.
By the way, we’re in this together, for the long haul.
Our company was founded specifically to generate much-needed money for targeted longevity research. Since profits benefit life-extending research, when you join our mission by using our breakthrough specialty anti-aging products, you can feel good about contributing to research… while contributing to your wellness and longevity at the same time.
And did I mention we developed TeloSC with my longevity in mind? Yes, we not only manufacture and distribute TeloSC… but use it as well. We know consuming the same high quality products designed for our own use… is great for you too.
You don’t want to be without TeloSC™
Here’s all you need to do: Have your credit card handy or use PayPal and click on the ‘Add to Cart’ button below Act now and I’ll send you free, the most impactful longevity program on the planet.
It’s value? Priceless!
Because it can easily shave 5-15 years off your “biological age” with hardly any effort.
You can download it immediately, the second you agree to your TeloSC trial.
I know that’s generous. But hold on, I’m about to get crazy generous here.
Your FREE Gift for Making the Choice to Win the Battle against Aging
By ordering right now, you’ll also become part of an exclusive “Life Extension” community. Normally it’d cost you $75 to get in on this. But as a valued TeloSC customer, you’ll automatically be included in this for FREE.
I had to pull some strings for you, because the benefits are huge.
Do the Other Guys Offer You This?
I know it’s easy to make claims.
But I’m so confident in TeloSC…
I protect you with an Unconditional 365-day
'No-Stress-Is-Best’ Money-Back Guarantee
If you aren't 100% happy for ANY reason, I’ll return every penny… no questions asked. Plus, I promise to refund that money within ONE business day… so there’re zero hassles.
Some think I'm taking big chances with this generous guarantee, but the way I see it I'm taking NO chance. I’m confident you’ll love this product so much… you'll never let it go.
Look, TeloSC works like crazy for most of us. Thousands of delighted clients used a weaker formula with rave reviews. It works for me, and I expect it’ll do the same for you.
The sooner you start TeloSC, the sooner you’ll look and feel like a “Younger You.”
It’s up to you – order TeloSC today and slow your aging to a crawl… and even rejuvenate yourself… or ignore this offer and continue aging before your time.
Click on the ‘Order Now’ button right now to control your aging… before it wrecks you.
But only do this if you're serious about wanting a more vigorous sex life… more radiant skin… more quality years to spend with your grandkids…
You must admit, this is by far the most generous, risk-free and easiest way to get on the road to wellness.
And the bonus materials are all yours to keep… no matter what you decide later.
So look and feel younger now. Waiting just keeps aging you. DO NOT get left behind. Click on the ‘Add to Cart’ button before you turn a minute older.
Don’t forget, when you harness the power of telomere and stem cell biology with TeloSC, you can enjoy MORE of what you deserve… starting now.
… More Life.
Investing in the revolutionary TeloSC is the smart way to go.
Monthly Life Extension Magazine® filled with global medical research results, scientific reports, and cutting-edge health information.
Disease Prevention and Treatment book ($69.95 cover price). This 1,406-page reference guide presents cutting-edge prevention and treatment protocols for 130 different diseases of aging. (Restricted to US customers. International customers may get the online version)
25%–50% Savings on over 400 science-based, premium-quality Life Extension supplements. All formulated to help you stay younger and healthier longer. And many more benefits.
We want your business for life. Another reason for our competition to hate us…
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What would you do with an extra twenty or thirty youthful energetic years? What would you give for them?
Before you know it, 100 will be the new 50. Find out why this is your destiny and how to help ensure it. (PDF Edition)
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Robert B, Irvington NJ
My name is Robert, and I am 34 years of age. I have been using TeloSC, for only a month, but within that month, I noticed that my health has dramatically improved, more than I ever could have imagined. I feel a lot healthier and stronger. I have more energy and vigor now with my workouts as well. I was a very healthy person before, but since using TeloSC, my health is now off of the charts. This is an amazing product, and I would recommend it to anyone who is 30 and over. I still take all of my regular supplements as well, such as my multivitamins, and my fish and krill oils. Again, I felt good before, but TeloSC, really put me over the top. I trust it with my life.
Don Evans, Cape Coral FL
My better half and I have been taking TeloSC for about 6 months. We have found positive results in our health. We would like to see if we can market/sales this product via the internet for on a commission basis? If so would you please point us to the person(s) that I can talk to so that we may get started?
Greta B., Los Angeles, CA
"As a person who has been on the cutting edge of MANY fitness protocols and who was a key part of the initial launch of TA-65 I know this category like the back of my hand. TeloSC is the next evolution of longevity solutions and NOTHING combines telomere support with stem cell support. This makes all of the other products obsolete. It's like APPLE compared to IBM. Technology changes with the times and so do supplements."
Doug Malewicki, Irvine, CA
I have been taking 2 TeloSC a day (maybe not super precisely on exactly two every day), but lately making sure I take my 2 a day BECAUSE of what I am noticing & I like it!
#1 - For a month now I have been able to run the entire 5.7 mile loop with 800' of climbs on my weekly Wednesday Whiting Ranch outing. For the last few year, I was power hiking the final long uphill. Seems I now have the capability to trot it up all the way without any kind of special exertion required. I think it has been 7 or 8 years since I could do that??
This past Sunday I ran the 14.2 mile loop that goes up Shady Canyon, then up Bommer Canyon, across Bommer Ridge to Laguna Coast Wilderness, through the upper Nix nature center trails and back down Quail Hill to the start. I probably have that trail run loop 3 or 4 times a year since Bommer was finally opened to the public back in 2011 and enabled the full loop. Sometimes we do it in the reverse direction.
I had to dig through all my Garmin GPS data saved on the Garmin Connect website to verify my times over the years. They were all between 4 hrs and 5 minutes and 4 hrs and 14 minutes. Sunday I did it in 3:35:55 WTF (Why That's Fascinating)!! This run included the usual photo stops with our lady trail running friends and other little breaks. The main difference was that I noticed that I could run up all the many steep rolling hills for quite a bit longer distance before having to switch to power walking mode.
Oh - the WTRS (Winter Trail Run Series) 12K race was on January 9th. Was my best time in 3 years. I did not feel like I was pushing hard either. Was enjoying my pace.
So the question is the TeloSC doing something good to the Geezer's body or have I been training harder (nah) to get these interesting results.
TeloSC did a number of good things for me. The first thing I noticed was the spots on the backs of my hand completely cleared up and disappeared. This was a very big deal because the spots were really small sores which caused me some pain and they were an unpleasant sight.
I had a bad bicycle accident in 1992 and sustained a high energy break to my right leg. I had a great doctor and was able to resume running and bicycling for many years. Unbeknownst to me, my leg had been "jammed" into my hip, causing deterioration of the hip joint. I began to experience joint pain in my hip and my doctor started advising me to consider hip replacement. This was three years ago. I have been taking TeloSC and InflaGene during this period and am happy to report that the joint pain has decreased, and, even though I give my hip a serious workout every day, I feel that the hip replacement surgery has been delayed for the foreseeable future and may not be necessary at all.
Lastly, since taking TeloSC, I have noticed my hair color has shifted from white/gray to more of its original color which is blond. This is a minor improvement compared to the other two, but still a welcome change.
I am responsible for taking GOOD care of myself. As such taking TeloSC was a delight to me. YES, I will enjoy a fine quality of life as I will continue taking products from MaxLife.
RJ., Wilmington, DE
I have been fortunate. Most of my biomarkers are in healthy ranges, and I have been doing a lot for many years to get them and keep them there. Even so, since taking TeloSC, my already good blood glucose level dropped by 11% since my previous reading, and my HDL level increased slightly, even though my total cholesterol dropped from 154 to 146. My LDL level dropped by over 11% as well. When total cholesterol drops, you would expect both HDL and LDL to drop accordingly. So my results are positive.
Click links to view details..
TeloSC™ acts on longevity genetic pathways to support stem cells and stem cell niches. Its ingredients are proven to extend animal life span. TeloSC™ supports your critical telomeres, stem cells and stem cell environment. Helps support cell, cardiovascular, immune, metabolic, and neural health and is an mTOR inhibitor.* Patent pending
Why is TeloSC™ Your Most Effective Supplement Available?
All the organs and differing tissues of the body appear to have adult stem cells available for regenerating cells in case of injury or disease.
As we age most adult stem cell populations either decline in number and/or lose the ability to differentiate into functional tissue-specific cells. For example, cardiac muscle stem cells exist but, the elderly have only one half the number of cardiac stem cells found in young people. Thus, adult stem cells become more and more dysfunctional with age, which progressively increases organ and tissue dysfunction with age.
There are many examples revealing the role of adult stem cells in aging. First, the outer surface of your skin continuously sloughs off dead cells, so that adult stem cells must continuously replenish the dying skin cells to maintain the skin as an effective protective barrier to the outside world. With age, there are progressively fewer functional skin stem cells, so cell turnover in the skin slows, leading to thinner, dryer skin that loses its elasticity and youthful beauty.
Second, hair also thins and goes grey, as functional follicle stem cells decline, and the adult stem cells generating hair color also decline.
Third, the differing adult stem cells that maintain the tissues composing skeletal muscle, pancreas, heart, bone, liver, kidney, and the immune system lose functional capacity, raising the potential for decline in tissue function or outright failure with age.
As a final example, the five senses: sight, hearing, smell, taste, and touch slowly wane with age as the declining stem cell populations responsible for maintaining these functions are unable to fully replenish the sensory neurons after injury and random cell death.
Look Younger, Feel Better and Improve Your Health with TeloSC™
Based on recent discoveries involving telomeres, stem cells and genes, TeloSC is designed to slow the aging process and help your body function more like a young person’s. Until now there was not much you could do about it. TeloSC rejuvenates adult stem cells and their micro-environments.
Developed by experts in the anti-aging field, the proprietary blend of TeloSC’s ingredients are proven to double maximum lifespan of an animal model. No other supplement beats these results.
Help Rejuvenate Your Body by Boosting Your Own Stem Cells
As a child, we are protected from the ravages of aging and can rapidly recover from injury or illness, because of the young regenerative stem cells of children have a superior ability to repair and regenerate most damaged tissues. As we age, our stem cell populations become depleted and/or slowly lose their capacity to repair. Moreover, the micro-environment (i.e. niches) around stem cells becomes less nurturing with age, so cell turnover and repair are further reduced. This natural progression occurs so slowly that we are barely aware of it. But we start noticing our body changes in our 20s, 30s, 40s, and especially after 50 years of age.
TeloSC helps adults regain their youthful regenerative potential by stabilizing telomeres and stem cell function.
TeloSC™ works differently than other products on the market
You may have seen a number of products advertised as stimulating or enhancing the number of stem cells. Each person only has a limited number, so using them up faster may not be a good strategy. TeloSC is about improving the effectiveness and longevity of your stem cells as well as preserving the stem cell micro-environment. The micro-environment declines with age due to declines in capillary density and increases in basal inflammation, fibrosis, toxic waste products, and fat cells.
An effective stem cell therapy must address the declines in micro-environment, as stem cells will not respond well in a harmful or toxic environment. That is exactly what TeloSC is designed to do and is one of only two products to do so.
Harness the Power of Your Own Stem Cells
Millions of people suffer from chronic aging and disease conditions. Based on international scientific studies in many academic and industry laboratories, there is new hope that many of the conditions afflicting mankind can someday be cured or greatly improved using stem cell regenerative medicine. TeloSC offers a way to receive some of the benefits of stem cell therapy today by improving the effectiveness of your own adult stem cells.
TeloSC’s ingredients were given to healthy volunteers in a pre-clinical study, and cholesterol tests and blood pressure monitoring were performed before and after treatment to see if the treatment changed cholesterol or blood pressure profiles. In the lab testing, there was a significant trend toward reductions in total cholesterol, LDL, and triglycerides with the herbal treatment. These trends would likely have been statistically significant if a larger sample size were used. A formal study is planned.
We will check volunteers via a double-blind, placebo-controlled clinical trial using before and after TeloSC treatment for changes in blood pressure. Finally, trial volunteers will also be tested for blood glucose levels before and after TeloSC treatment.
Higher levels of HDL cholesterol, reduced blood pressure, and reduced fasting blood glucose are all independent indicators of longevity, so these preliminary results should further suggest that TeloSC may reduce all-cause mortality in humans as is the case for Drosophila (fruit flies).
Beneficial Effects of TeloSC™ based on the literature of its components:
1. What is the preferred dose of TeloSC™ and when should it be taken?
If you are 125 pounds or less or in your 20s, then it may be best to only take one capsule of TeloSC per day preferably with a meal. For those over 125 pounds and over 30 years of age, we recommend two capsules per day preferably taken at breakfast and dinner. Note that the recommendation to take TeloSC at meals is not due to any problems with taking the supplement on an empty stomach. Rather, the pterostilbene in TeloSC acts as an insulin sensitizer to help glucose cross into your cells and thus reduces the spike in glucose and insulin that routinely occurs after a meal. It is also best to take the two capsules at different meals, as the 105 minute half-life of pterostilbene in the blood stream means that less of the insulin sensitizer is around after 4 hours and even less after 8 hours. That said, if you are one of the many people who can only remember to take your pills once per day, then it is best to take two capsules at the same time, preferably at one of your meals.
2. What improvements might I experience taking TeloSC™?
Some of the benefits of TeloSC such as a slowing of the aging process may not be immediately apparent, however, there have been many reported beneficial effects on the first version including:
Skin elasticity can be tested easily at home without equipment using the pinch test. One 60+ male on the first version of TeloSC claims that he went from 7-8 sec on the pinch test to 2-3 sec in less than two years.
We do not make any medical claims for TeloSC, however, you might find it interesting to do before and after blood tests with your doctor and monitor LDL and HDL cholesterol, fasting glucose, fasting insulin and C-Reactive Protein (CRP) which is an indicator of chronic inflammation. Another test you may want to periodically check yourself is blood pressure.
Note that TeloSC is not meant as a treatment or preventive for hypertension, cholesterol problems, diabetes, or inflammation. However, TeloSC can help with keeping these blood parameters at more healthful levels for those already in the normal range.
If you experience one or more of these benefits and/or some other benefit that is not listed, please let us know using our Contact Form.
I read that many herbs are not well absorbed, and therefore do little good. Is that true for the ingredients in TeloSC?
What you are referring to in “bioavailability,” or how well compounds are taken up into and absorbed by your cells. Standard versions of three of our key ingredients; milk thistle, astragalus root extract and Pterocarpus marsupium which contains pterostilbene among other important compounds, are poorly bioavailable.
Recognizing how critical bioavailability is to your optimal health (and to your pocketbook), those key ingredients were made 5-10 times more effective through the use of two patent-pending processes.
How does TeloSC™ compare to TeloSC?
TeloSC is an improved, more bioavailable and more potent version of TeloSC, our previous formulation.
How does TeloSC™ compare to the more popular telomere products?
We believe TeloSC is one of the, if not the most effective telomere health products on the market. To the best of our knowledge, there have been no clinical studies comparing any of the products to one another.
We do know that even though our manufacturing costs compare with the higher priced products, we have kept our prices much lower in order to make TeloSC affordable to nearly everyone interested in optimal health and longevity.
3. How does TeloSC™ compare to the widely available antiaging supplement resveratrol?
Much research has been done on Resveratrol and it has been in the news during the past few years. While the original experiment treating mice with resveratrol did generate somewhat longer lived mice, later experiments have given mixed results in extending mouse lifespan, as is also the case with longevity experiments in worms and fruit flies.
One likely reason for these variable results is that resveratrol is a very unstable compound with only a 14 minute half-life in the blood stream. In contrast, pterostilbene, a close resveratrol analog, has a half-life of 105 minutes (7.5 fold higher) and is one of the principle components found in TeloSC. This means that by the time you have lost 50% of pterostilbene, you have lost more than 99% of resveratrol! Moreover, neither resveratrol nor pterostilbene are very bioavailable without the proprietary technology used in TeloSC. While the pterostilbene is the most prevalent resveratrol analog in TeloSC, there is another potent resveratrol analog in TeloSC called marsupsin, which acts synergistically with pterostilbene.
4. Does TeloSC contain stem cells?
No, they do not contain stem cells. TeloSC supports the stem cells which you have naturally in your body in addition to supporting your cells’ telomeres. It is a true breakthrough anti-aging product designed for full body rejuvenation.
5. In picking the herbal extracts for TeloSC™, were ingredients chosen that affect the same genes that differed in the Methuselah flies?
The Methuselah flies are fruit fly colonies that were selectively bred for over 20 years for healthy longevity. They live 4X longer than normal flies due to selectively bred changes in gene expression. The reason this is important is that fruit flies are a surprisingly good model for human longevity genes. The genes attributed to longevity are approximately 90% similar between humans and fruit flies. The method used to pick the ingredients chosen for TeloSC is described in Fine-Turn Your Longevity Genes. The gene expression changes in Methuselah flies did give many targets for intervention into the aging process. The surprise was that there were so many genes that changed in Methuselah flies. This naturally led to the idea that many targets would have to be hit simultaneously if one were to succeed in inducing a major change in the rate of aging. That was the genesis of the wide spectrum TeloSC, which may finally have the potential to target a critical threshold of the genes involved in aging. While the selection of ingredients for TeloSC had many constraints beyond targeting Methuselah genes, the final product was found to alter many of the highest scoring Methuselah genes using our licensed proprietary AI software. This fact plus the fly longevity data gives us high confidence that we are on the right track. A third party’s subsequent human Field Trial showed many positive results which are all independent measures of long healthspan and lifespan.
I read that many herbs are not well absorbed, and therefore do little good. Is that true for the ingredients in TeloSC?
What you are referring to is “bioavailability,” or how well compounds are taken up into and absorbed by your cells. Standard versions of three of our key ingredients; astragalus root extract, milk thistle, and pterocarpus marsupium which contains pterostilbene among other important compounds, are poorly bioavailable.
Recognizing how critical bioavailability is to your optimal health (and to your pocketbook), those key ingredients were made 5-10 times more effective through the use of two patent-pending processes.
6. What are the potential interactions between TeloSC™ and medications?
If you are taking any of the following drugs, then you should consult your physician before taking herbal, vitamin or other nutritional supplements. It may be necessary to monitor and adjust some of the medications as needed.
7. How safe is TeloSC™ and what are the side effects?
All of the individual herbal extracts in TeloSC have 40 years or longer history of human use without significant reported side effects. Moreover, both animal and human trials have been published on the safety and effectiveness of the individual herbal extracts. If you believe you have experienced any side effects while using TeloSC please report them to us using our Contact form.
Inside the nucleus of a cell, our genes are arranged along twisted, double-stranded molecules of DNA called chromosomes. At the ends of the chromosomes are stretches of DNA called telomeres, which protect our genetic data, make it possible for cells to divide, and hold some secrets to how we age and get cancer.
Telomeres have been compared with the plastic tips on shoelaces, because they keep chromosome ends from fraying and sticking to each other, which would destroy or scramble an organism's genetic information.
Yet, each time a cell divides, the telomeres get shorter. When they get too short, the cell can no longer divide; it becomes inactive or "senescent" or it dies. This shortening process is associated with aging, cancer, and a higher risk of death. So telomeres also have been compared with a bomb fuse.
Nature Reviews Molecular Cell Biology 8, 703-713 (September 2007) |doi:10.1038/nrm2241
ARTICLE SERIES: Stem cells
How stem cells age and why this makes us grow old
Norman E. Sharpless1 & Ronald A. DePinho2
Recent data suggest that we age, in part, because our self-renewing stem cells grow old as a result of heritable intrinsic events, such as DNA damage, as well as extrinsic forces, such as changes in their supporting niches. Mechanisms that suppress the development of cancer, such as senescence and apoptosis, which rely on telomere shortening and the activities of p53 and p16INK4a, may also induce an unwanted consequence: a decline in the replicative function of certain stem-cell types with advancing age. This decreased regenerative capacity appears to contribute to some aspects of mammalian ageing, with new findings pointing to a 'stem-cell hypothesis' for human age-associated conditions such as frailty, atherosclerosis and type 2 diabetes.
From Wikipedia, the free encyclopedia
The stem cell theory of aging is a new theory which was formulated by several scientists and which postulates that the aging process is the result of the inability of various types of stem cells to continue to replenish the tissues of an organism with functional differentiated cells capable of maintaining that tissue's (or organ’s) original function. Damage and error accumulation in genetic material is always a problem for systems regardless of the age. The number of stem cells in young people is very much higher than older people and this cause a better and more efficient replacement mechanism in the young contrary to the old. In other words, aging is not a matter of the increase of damage, but a matter of failure to replace it due to decreased number of stem cells. Stem cells decrease in number and tend to lose the ability to differentiate into progenies or lymphoidlineages and myeloid lineages.
Maintaining the dynamic balance of stem cell pools requires several conditions. Balancing proliferation and quiescence along with homing (See niche) and self-renewal of hematopoietic stem cells are favoring elements of stem cell pool maintenance while differentiation, mobilization and senescence are detrimental elements. These detrimental effects will eventually cause apoptosis.
There are also several challenges when it comes to therapeutic use of stem cells and their ability to replenish organs and tissues. First, different cells may have different lifespans even though they are originated from the same stem cells (See T-cells and erythrocytes), meaning that aging can occur differently in cells that have longer lifespans as opposed to the ones with shorter lifespans. Also, continual effort to replace the somatic cells may cause exhaustion of stem cells.
Volume 132, Issue 4, 22 February 2008, Pages 681–696
Stems Cells and the Pathways to Aging and Cancer
The aging of tissue-specific stem cell and progenitor cell compartments is believed to be central to the decline of tissue and organ integrity and function in the elderly. Here, we examine evidence linking stem cell dysfunction to the pathophysiological conditions accompanying aging, focusing on the mechanisms underlying stem cell decline and their contribution to disease pathogenesis.
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